P30 Lung injury and its prognostic significance in acute liver failure
نویسندگان
چکیده
منابع مشابه
Elevated troponin I and its prognostic significance in acute liver failure
INTRODUCTION Acute liver failure (ALF) is a life-threatening multisystem illness complicated by multiple organ failure (MOF) and haemodynamic disturbances. Morbidity and mortality remains high and various prognostic and scoring models are in use to predict outcome. A recent observation in a large cohort of ALF patients suggested a prognostic value of troponin I (cTnI) and its role as a marker o...
متن کاملDesferrioxamine attenuates minor lung injury following surgical acute liver failure.
Acute liver failure (ALF) can be complicated by lung dysfunction. The aim of this study was to test the hypothesis that inhibition of oxidative stress through iron chelation with desferrioxamine (DFX) attenuates pulmonary injury caused by ALF. 14 adult female domestic pigs were subjected to surgical devascularisation of the liver and were randomised to a study group (DFX group, n = 7), which re...
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UNLABELLED Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the United-States. The aim of the study was to describe serum immune profiles associated with acute DILI, to investigate whether there are profiles associated with clinical features or types of DILI and/or with prognosis, and to assess temporal changes in levels. Twenty-seven immune analytes were meas...
متن کاملPlasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance.
BACKGROUND Angiopoietin-2 is a proinflammatory mediator of endothelial injury in animal models, and increased plasma angiopoietin-2 levels are associated with poor outcomes in patients with sepsis-associated acute lung injury. Whether angiopoietin-2 levels are modified by treatment strategies in patients with acute lung injury is unknown. OBJECTIVES To determine whether plasma angiopoietin-2 ...
متن کاملEarly detection of type III procollagen peptide in acute lung injury. Pathogenetic and prognostic significance.
The fibroproliferative reaction to acute lung injury may limit restoration of normal lung function and increase mortality in patients with acute lung injury. A biologic marker of collagen synthesis in the lung may be useful for studying the pathogenesis of acute lung injury and for identifying patients with acute lung injury who are at high risk for death and might benefit from new therapeutic ...
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ژورنال
عنوان ژورنال: Gut
سال: 2011
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2011-300857a.30